Indegene Inc. is a technology-led healthcare solutions provider. It combines deep industry expertise with
fit-for-purpose technology in an agile and scalable operating model, and offers research and development, and
management services to healthcare and pharmaceutical enterprises. Many of the leading global healthcare
organizations rely on its technology to deliver effective and efficient clinical, medical, and commercial
outcomes every day. From strategy to execution, Indegene Inc. enables healthcare organizations to be future
ready. It was founded in 1998 and is based in Bangalore, India. Indegene has offices in North America, Europe,
China and India.
Indegene required an AS2 gateway to be deployed for one of the largest pharmaceutical corporations in the world,
and to integrate its solutions running on the AWS cloud seamlessly. The main flow of messages was with the clients
safety database and Indegene’s case processing technology and operations. The requirement was to accelerate and
scale the case processing services for the customer with the volume of messages per month expected to be around
400,000 messages. Native operation on the Amazon Web Services (AWS) cloud, was a distinct advantage sought after
in a solution.
Indegene soon found out and investigated the MFT Gateway solution by Aayu Technologies LLC, and was happy to
evaluate it with a free sign up and a free trial. During the evaluation, Indegene configured the hosted Software
as a Solution (SaaS) version of the MFT Gateway to integrate with an AWS S3 bucket of an external organization.
This allowed Indegene to try out the system and understand its ease of use and the advantages of its AWS native
Indegene requested Aayu Technologies to deploy the MFT Gateway solution into an isolated AWS account under its
control, and within the required geographic region. This allowed Indegene to be in full control and ownership
of all data being exchanged and stored, to meet the regulatory requirements.
The deployment also allowed customizations required by Indegene, specifically to use on-rest encryption of files
on S3 storage, and use of a dedicated Virtual Private Cloud (VPC) for outbound messages, utilizing a static IP.
To adhere with the strict access control requirements, AWS Web Application Firewall (WAF) was utilized to impose
IP based access controls to different components of the deployment such as the web console, AS2 endpoints and
REST APIs. The customizations also included a Simple Queue Service (SQS) notification to notify Indegene systems
of events, which the target systems then used to fetch message payloads from S3. Using the S3 integration
capabilities, the Indegene systems could both send and receive messages over AS2 by simply copying to, and
reading from the allocated S3 storage bucket.
The system was moved into production from April 2021 and is successfully processing hundreds of thousands of
messages per month as expected, while being under the full control and ownership of Indegene. The success of
this initial deployment led Indegene to use the same MFT Gateway for a second deployment in production from